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Clostridium Difficile Colitis

Posted Monday 24 September 2007 - 10:47 AM by David Chan

First Line Drugs

  1. METRONIDAZOLE (J01XD01)

Second Line Drugs

  1. VANCOMYCIN (J01XA01)

Reference

Comments/Instructions

metronidazole 250 mg, qid x 10 days $1.11/10 days

Second-line therapies:

vancomycin 125 mg, qid x 10 days $262.24/10 days

-If possible stop antibiotic(s) responsible for the Clostridium difficile superinfection.

-Avoid antimotility agents (loperamide and diphenoxylate).

-Relapse rate is as high as 20%.

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