- PCP (Pneumocystis Carinii Pneumonia)- Prophylaxis

PCP (Pneumocystis Carinii Pneumonia)- Prophylaxis

Posted Monday 24 September 2007 - 11:03 AM by David Chan

First Line Drugs

TRIMETHOPRIM (J01EA01)

Second Line Drugs

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INDOMETACIN (M01AB01)

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Reference

http://oscarmcmaster.org:25300/oscarResource-Pl...

Comments/Instructions

Trimethoprim/ sulfamethoxazole 160 mg/800 mg tablet, once daily or 3 times/week $0.12/tablet

Second-line therapies:

1. diaphenylsulfone 100 mg, 3 times a week $0.59/week

or 50-100 mg, once daily $0.68-1.37/week

AND

pyrimethamine 50 mg, twice weekly $4.28/week

2. pentamidine aerosolized 300 mg, once/month via Respigard II nebulizer $68.61/month

Initial dose 60 mg per dose x 5 doses over 2 weeks via Fisoneb nebulizer $68.61/2 weeks

Maintenance 60 mg, every 2 weeks via Fisoneb nebulizer $68.61/2 weeks

-Prophylaxis is indicated for any patient with HIV with: a history of PCP; a CD4 count below 0.2 x 10(9) cells/L; a CD4 count below 0.3 x 10(9) cells/L and signs of immunosuppression; or a CD4 count below 14%.

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