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cancer-related fatigue

Posted Friday 20 August 2010 - 17:23 PM by David Chan

First Line Drugs

  1. METHYLPHENIDATE (N06BA04)

Reference

Comments/Instructions

There is increasing evidence that psychostimulant trials provide evidence for improvement in CRF at a clinically meaningful level. There is still a requirement for a large scale RCT of methylphenidate to confirm the preliminary results from this review. There is new safety data which indicates that the haemopoietic growth factors are associated with increased adverse outcomes. These drugs can no longer be recommended in the treatment of CRF. Readers of the first review should re-read the document in full.

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