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Quinine

Posted Tuesday 23 February 2010 - 15:08 PM by David Chan (HIGH significance )

Quinine

ATC Code: P01BC01

Warning

FDA Orders Unapproved Quinine Drugs from the Market and Cautions Consumers About "Off-Label" Use of Quinine to Treat Leg Cramps Since 1969, FDA has received 665 reports of adverse events with serious outcomes associated with quinine use, including 93 deaths. Quinine drugs are associated with serious side effects, such as cardiac arrhythmias, thrombocytopenia (a decrease in blood platelets that can cause hemorrhage or clotting problems), and severe hypersensitivity reactions. There is also the potential for serious interactions between quinine drugs and other drugs, and there are conditions under which quinine should not be used.

Evidence

Good

Reference

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